Status:

TERMINATED

Efficacy of QVAR vs Flovent Diskus on Small Airways in Poorly Controlled Asthmatic Adolescents/Adult Patients

Lead Sponsor:

Teva Branded Pharmaceutical Products R&D, Inc.

Conditions:

Asthma

Eligibility:

All Genders

12-70 years

Phase:

PHASE4

Brief Summary

The primary objective of this study is to evaluate the effect of Beclomethasone dipropionate HFA on small airways compared to Fluticasone propionate powder for inhalation administered twice daily to p...

Eligibility Criteria

Inclusion

  • Poorly controlled asthma;
  • Average use of over 2 puffs of albuterol per day in the previous 7 days OR Having symptoms of asthma on 5 of the last 7 days OR Awakening at night due to asthma at least once in the previous 7 days OR Having been treated with a course of oral or intravenous steroids at least once in the last 3 months.

Exclusion

  • Subjects receiving escalating doses of immunotherapy, oral immunotherapy or short course (rush) immunotherapy for rhinitis;
  • Requires beta-blockers, MAO inhibitors, tricyclic antidepressants, oral or intranasal anticholinergics;
  • History and/or presence of any non-asthmatic acute or chronic lung disease, including but not limited to bronchitis, emphysema, active tuberculosis, bronchiectasis or cystic fibrosis;
  • History and/or presence of any clinically significant cardiovascular disease, clinically significant hepatic, renal, or endocrine dysfunction, stroke, uncontrolled diabetes, hyperthyroidism, convulsive disorders, neoplastic disease other than basal cell carcinoma, and significant psychiatric disease.

Key Trial Info

Start Date :

January 31 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 31 2006

Estimated Enrollment :

49 Patients enrolled

Trial Details

Trial ID

NCT00071552

Start Date

January 31 2004

End Date

July 31 2006

Last Update

November 24 2021

Active Locations (1)

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1

National Jewish Medical and Research Center

Denver, Colorado, United States, 80206