Status:
COMPLETED
Brain Activation During Simple Vocal Behaviors
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Auditory Perception
Eligibility:
All Genders
Brief Summary
This study will examine the central regions and brain activation patterns associated with simple vocal behaviors under conditions of normal auditory feedback-when people hear themselves speak. Such fe...
Detailed Description
Auditory feedback plays a uniquely prominent role in the learning and maintenance of human voice control. Yet much of what is known about central voice motor control has come from research in non-huma...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Males and females of any race or ethnicity will be eligible to participate in this study.
- Volunteers must be between the ages of 18 and 45 with normal hearing and voice function. Participants will be further selected for having a steady heart rate. A history of voice training is not required, but participants must be able to produce grossly independent voice F0 and amplitude changes.
- EXCLUSION CRITERIA:
- Contraindications to participation include: pregnancy, cardiac pacemaker or auto defibrillator, artificial heart valve, neural pacemaker, surgical metal clips in the brain, eye, or on blood vessels, cochlear implants, ocular implants or foreign bodies such as metal shavings or splinters, insulin pump, implanted drug infusion device, shrapnel, bullet or shot wound, and tattooed makeup. Participants will be screened with the NMR Center Safety Screening Questionnaire which also includes items such as intraventricular shunts, transdermal medication patches, wire sutures, bone/joint pins, screws, nails, or plates, and body piercings. Given that surgical staples, orthopedic pins, orthodontic braces and dental implants are no longer considered absolute contraindications in MRI, Dr. Saxon or Dr. Kearney will approve or disapprove participation in the study based on their judgment of the MR compatibility of these items, using published guides including those referenced above.
- Volunteers will be also excluded if they are found to be pregnant, report any tendency toward claustrophobia or are unable for any reason to lie still within an MR scanner.
Exclusion
Key Trial Info
Start Date :
October 1 2003
Trial Type :
OBSERVATIONAL
End Date :
October 1 2004
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT00071734
Start Date
October 1 2003
End Date
October 1 2004
Last Update
March 4 2008
Active Locations (1)
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1
National Institute of Neurological Disorders and Stroke (NINDS)
Bethesda, Maryland, United States, 20892