Status:
TERMINATED
A Study of Effectiveness and Safety of Abciximab in Patients With Acute Ischemic Stroke (AbESTT-II)
Lead Sponsor:
Centocor, Inc.
Collaborating Sponsors:
Eli Lilly and Company
Conditions:
Cerebrovascular Accident
Brain Ischemia
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of this study is to determine the effectiveness of abciximab in the treatment of acute ischemic stroke.
Detailed Description
Abciximab is a drug that prevents platelets from sticking together and forming a clot. There are limited studies using abciximab in the treatment of strokes. This phase III, multicenter, randomized, d...
Eligibility Criteria
Inclusion
- Patients with diagnosis of acute ischemic stroke with onset within 5 hours and 30 minutes before randomization and planned treatment initiation within 6 hours of onset
- After 600 patients are enrolled in previous criteria, the new criteria for enrollment will be, patients with diagnosis of acute ischemic stroke with onset within 4 hours and 30 minutes before randomization and planned treatment initiation within 5 hours of onset
Exclusion
- Patients who had participation in another study with an investigational drug or device within the last 30 days, prior participation in the present study, or planned participation in another trial
- Patients with symptoms suggestive of subarachnoid hemorrhage
- Female patients known to be pregnant, lactating, or having a positive or indeterminate pregnancy test
- Patients with neurological deficit that has led to stupor or coma
- Patients with minor stroke
Key Trial Info
Start Date :
October 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2005
Estimated Enrollment :
808 Patients enrolled
Trial Details
Trial ID
NCT00073372
Start Date
October 1 2003
End Date
December 1 2005
Last Update
May 17 2011
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.