Status:
TERMINATED
Helping HIV Infected Patients in South Africa Adhere to Drug Regimens
Lead Sponsor:
Johns Hopkins University
Collaborating Sponsors:
University of Cape Town
Conditions:
HIV Infections
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Three or more anti-HIV drugs are taken in combination as part of a treatment regimen. These drug regimens must be closely followed in order to be successful. Having a support person watch a patient ta...
Detailed Description
South Africa has one of the worst and fastest growing HIV epidemics in the world. Highly active antiretroviral therapy (HAART) has been shown both at the individual and public health levels to reduce ...
Eligibility Criteria
Inclusion
- HIV infected
- Viral load greater than 1000 copies/ml
- CD4 count of 200 cells/mm3 or less, or World Health Organization Stage 4 disease
- Living in the area of the study site
- Had a known address for more than 3 months
- Willing to nominate a treatment supervisor (a close family member, sexual partner, friend, or community volunteer) to observe daily ingestion of tablets
- Willing to disclose HIV status to a treatment supervisor and ready to commit to long-term antiretroviral therapy
- Acceptable methods of contraception
Exclusion
- Pregnant
Key Trial Info
Start Date :
February 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2008
Estimated Enrollment :
274 Patients enrolled
Trial Details
Trial ID
NCT00076804
Start Date
February 1 2005
End Date
September 1 2008
Last Update
March 27 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Cape Town
Cape Town, South Africa, 7925