Status:
COMPLETED
Timing of Voluntary Movement in Patients With Tourette Syndrome and Chronic Tic Disorder
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Tourette Syndrome
Tic Disorders
Eligibility:
All Genders
18-65 years
Brief Summary
This study will examine how the brain controls movement in people with Tourette syndrome and chronic tic disorder to determine if the timing of movement is important in whether someone feels "in contr...
Detailed Description
OBJECTIVES: The purpose of this study is to determine how the subjective sense of willing and initiating an action is altered in patients with Tourette Syndrome and Chronic Tic Disorder. Although many...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Tic Patients:
- Patients will be men or women, ages 18-65, with a DSM-IV-TR diagnosis of TS or CTD. Patients will be screened in the NINDS Movement Disorders Outpatient Clinic, and will have neurological and physical examinations. They will be asked to abstain from alcohol and any medications for 24 hours before the study. All subjects participating in the studies will have a valid Clinical Center Medical Record Number.
- Normal Volunteers:
- Twenty-six normal controls will be included; controls will be screened in the NINDS Movement Disorders Outpatient Clinic, and will have neurological and physical examinations. They will be asked to abstain from alcohol and any medications for 24 hours before the study. All subjects participating in the studies will have a valid Clinical Center Medical Record Number.
- EXCLUSION CRITERIA:
- Patients younger than 18 years old or older than 65 years old will be excluded from the study.
- Tic Patients:
- Patients with neurological disorders other than TS or CTD
- Patients with Attention deficit hyperactivity disorder (ADHD)
- Patients who are not able to abstain from alcohol or medication affecting the central nervous system for 24 hours before the study
- Patients not capable of giving an informed consent
- Normal Subjects:
- Patients with neurological disorders or ADHD
- Patients who are not able to abstain from alcohol or medication affecting the central nervous system for 24 hours before the study
- Patients not capable of giving an informed consent
Exclusion
Key Trial Info
Start Date :
April 8 2004
Trial Type :
OBSERVATIONAL
End Date :
January 12 2009
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT00081419
Start Date
April 8 2004
End Date
January 12 2009
Last Update
July 2 2017
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892