Status:

COMPLETED

Helicobacter Pylori and Dry Eye

Lead Sponsor:

National Eye Institute (NEI)

Conditions:

Helicobacter Infections

Eligibility:

All Genders

Brief Summary

This study will examine whether infection with Helicobacter pylori bacteria may cause inflammation of the eye's surface. Although most people who are infected with H. pylori do not have symptoms, the ...

Detailed Description

Helicobacter pylori, one of the world's most prevalent pathogens, is a spiral-shaped, catalase-positive, Gram-negative rod with 4-6 sheathed flagella attached to one pole which allow for motility. The...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • Patients with ocular surface disease including aqueous or evaporative tear deficiency who are seropositive for H. pylori will be eligible. Controls will be adults without ocular surface disease who are seropositve for H. pylori.
  • EXCLUSION CRITERIA:
  • None listed.

Exclusion

    Key Trial Info

    Start Date :

    May 1 2004

    Trial Type :

    OBSERVATIONAL

    End Date :

    March 1 2005

    Estimated Enrollment :

    10 Patients enrolled

    Trial Details

    Trial ID

    NCT00083291

    Start Date

    May 1 2004

    End Date

    March 1 2005

    Last Update

    March 4 2008

    Active Locations (1)

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    National Eye Institute (NEI)

    Bethesda, Maryland, United States, 20892