Status:
RECRUITING
Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme
Lead Sponsor:
National Cancer Institute (NCI)
Conditions:
Glioblastoma Multiforme
Eligibility:
All Genders
18+ years
Brief Summary
This study will collect blood and urine samples from patients undergoing radiation therapy for glioblastoma multiforme (a type of brain tumor) to investigate the effects of this treatment on blood cel...
Detailed Description
BACKGROUND * Preliminary data generated from our pilot protocol 02-C-0064 suggests that the urinary VEGF and MMP level at the one month follow-up time point compared to the last on-treatment time poi...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Age greater than or equal to 18 years.
- Histologically confirmed supratentorial Glioblastoma multiforme.
- Karnofsky performance \>60.
- Patient must be a candidate for radiotherapy.
- Ability of subject or Legally Authorized Representative (LAR) to understand and the willingness to sign a written informed consent document.
- EXCLUSION CRITERIA:
- Patients with other cancers excluding non-melanomatous skin cancers or carcinoma in situ.
- Gliadel wafer placement at the time of surgery.
- Pregnancy because radiation has the potential for teratogenic or abortifacient effects.
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Exclusion
Key Trial Info
Start Date :
June 22 2004
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00083512
Start Date
June 22 2004
Last Update
December 31 2025
Active Locations (1)
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1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892