Status:
COMPLETED
The National CT Colonography Trial
Lead Sponsor:
American College of Radiology Imaging Network
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Colorectal Cancer
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
RATIONALE: New diagnostic procedures such as computed tomographic colonography may improve the ability to detect colorectal cancer and may provide a less invasive method of detection. PURPOSE: This c...
Detailed Description
OBJECTIVES: Primary * Compare the sensitivity of computed tomographic colonography (CTC) vs colonoscopy for detecting significantly large lesions (≥ 10 mm in diameter) in asymptomatic participants, ...
Eligibility Criteria
Inclusion
- Inclusion Criteria
- Male or female outpatients
- Aged 50 years or older
- Scheduled for screening colonoscopy
- Participant's signed informed consent
- Exclusion Criteria
- Symptoms of disease of the lower gastrointestinal tract, including
- Melanotic stools or/and hematochezia on more than one occasion in the previous six months
- Lower abdominal pain that would normally require a medical evaluation
- Inflammatory bowel disease and/or familial polyposis syndrome
- Serious medical conditions that would increase the risk associated with colonoscopy or are so severe that screening would have no benefit
- Pregnancy
- Previous colonoscopy within the past five years
- Anemia (hemoglobin less than 10 gm/dl)
- Positive fecal occult blood test (FOBT)
Exclusion
Key Trial Info
Start Date :
February 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 13 2010
Estimated Enrollment :
2600 Patients enrolled
Trial Details
Trial ID
NCT00084929
Start Date
February 1 2005
End Date
May 13 2010
Last Update
December 22 2020
Active Locations (14)
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1
Mayo Clinic Scottsdale
Scottsdale, Arizona, United States, 85259-5499
2
Moores UCSD Cancer Center
La Jolla, California, United States, 92093-0658
3
Jonsson Comprehensive Cancer Center at UCLA
Los Angeles, California, United States, 90095-1781
4
Veterans Affairs Medical Center - San Francisco
San Francisco, California, United States, 94121