Status:
COMPLETED
Joint Injections for Osteoarthritic Knee Pain
Lead Sponsor:
University of Wisconsin, Madison
Collaborating Sponsors:
National Center for Complementary and Integrative Health (NCCIH)
Conditions:
Osteoarthritis
Eligibility:
All Genders
40-70 years
Phase:
PHASE1
PHASE2
Brief Summary
The purpose of this study is to determine whether prolotherapy (PrT), a therapy based on injection of a sugar solution in and around the knee, can decrease pain and disability from knee osteoarthritis...
Detailed Description
OA is a common, debilitating condition for which there is no cure and no known cause. Prolotherapy (PrT) is an injection-based therapy for chronic musculoskeletal pain in which an irritant solution is...
Eligibility Criteria
Inclusion
- Pain from knee osteoarthritis that has impacted life for 3 months to 10 years
- X-ray results indicating knee osteoarthritis
Exclusion
- Knee osteoarthritis surgical candidate
- History of total knee joint repair
- Prior use of PrT
- Prior fracture of the knee joint
- Joint injection of steroids or other drugs within the past 3 months
- Rheumatoid or inflammatory arthritis
- Chronic use of narcotic medication
- Other chronic pain diagnoses
- diabetes mellitus
- Body mass index (BMI) greater than 45
- Unresolved litigation
- Pregnancy
- Co-morbidity that may interfere with the study
Key Trial Info
Start Date :
July 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2016
Estimated Enrollment :
98 Patients enrolled
Trial Details
Trial ID
NCT00085722
Start Date
July 1 2004
End Date
May 1 2016
Last Update
February 15 2019
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Northeast Family Medical Center
Madison, Wisconsin, United States, 53704
2
University of Wisconsin General Clinical Research Center
Madison, Wisconsin, United States, 53792