Status:
COMPLETED
Positron Emission Tomography Imaging of Dopamine Receptors Using the Tracer [11C]NNC-112
Lead Sponsor:
National Institute of Mental Health (NIMH)
Conditions:
Healthy
Eligibility:
All Genders
Phase:
PHASE1
Brief Summary
This study will investigate the use of \[11C\]NNC-112 in positron emission tomography (PET) scanning. PET is a technique that uses radioactive isotopes called tracers to provide images of the brain. I...
Detailed Description
Abnormalities in dopaminergic neurotransmission have been implicated in several neurodegenerative and psychiatric disorders, such as Parkinson's disease, schizophrenia, attention-deficit-hyperactivity...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA
- All subjects must be healthy and aged 18-70 years.
- EXCLUSION CRITERIA
- Current psychiatric disease, substance abuse or severe systemic disease based on history and physical exam
- Laboratory tests with clinically significant abnormalities
- More than moderate hypertension
- Any prior participation in other research protocols within the past year that involve radiation, with the exception of plain radiography studies (i.e., chest x-rays).
- Pregnancy and Breast Feeding
- Positive HIV test
Exclusion
Key Trial Info
Start Date :
July 1 2004
Trial Type :
INTERVENTIONAL
End Date :
March 1 2006
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00088517
Start Date
July 1 2004
End Date
March 1 2006
Last Update
March 4 2008
Active Locations (1)
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1
National Institute of Mental Health (NIMH)
Bethesda, Maryland, United States, 20892