Status:
COMPLETED
DNA Variations in the Gene in Young Patients With Wilms' Tumor
Lead Sponsor:
Children's Oncology Group
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Kidney Cancer
Eligibility:
All Genders
Up to 18 years
Brief Summary
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer. PURPOSE: Th...
Detailed Description
OBJECTIVES: Primary * Determine the presence of the A133S polymorphism in the RASSF1A tumor suppressor gene by screening germline DNAs of children with Wilms' tumor. * Determine the inheritance patt...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Diagnosis of Wilms' tumor OR
- Control participants matched for race, sex, and age
- No prior or concurrent history of cancer OR
- Parents of children involved in the study
- PATIENT CHARACTERISTICS:
- Not specified
- PRIOR CONCURRENT THERAPY:
- Not specified
Exclusion
Key Trial Info
Start Date :
August 1 2004
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
471 Patients enrolled
Trial Details
Trial ID
NCT00088803
Start Date
August 1 2004
Last Update
May 19 2016
Active Locations (232)
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1
University of Alabama at Birmingham Comprehensive Cancer Center
Birmingham, Alabama, United States, 35233
2
University of South Alabama Cancer Research Institute
Mobile, Alabama, United States, 36604
3
Phoenix Children's Hospital
Phoenix, Arizona, United States, 85016
4
Arizona Cancer Center at University of Arizona Health Sciences Center
Tucson, Arizona, United States, 85724