Status:
TERMINATED
S0229, Pulmonary Rehabilitation Education w/wo Exercise Training in Improving Physical Function in Patients Who Are Undergoing Chemo & RT for Locally Advanced Lung Cancer
Lead Sponsor:
SWOG Cancer Research Network
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Lung Cancer
Pulmonary Complications
Eligibility:
All Genders
Phase:
NA
Brief Summary
RATIONALE: Pulmonary rehabilitation education and exercise training may improve physical function and quality of life in patients who are receiving treatment for lung cancer. PURPOSE: This randomized...
Detailed Description
OBJECTIVES: * Compare improvement in physiologic function, in terms of exercise tolerance, in patients with inoperable locally advanced lung cancer undergoing chemoradiotherapy and randomized to pulm...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Histologically or cytologically confirmed single, primary bronchogenic lung cancer
- Inoperable, locally advanced disease (unresectable stage IIIA OR stage IIIB disease)
- The following histologies are eligible:
- Adenocarcinoma
- Large cell carcinoma
- Squamous cell carcinoma
- Non-lobar and non-diffuse bronchoalveolar carcinoma
- Small cell lung cancer
- Must have received chemotherapy (platinum based) and radiotherapy for locally advanced unresectable lung cancer
- Must have achieved a complete response, partial response, or stable disease after treatment
- PATIENT CHARACTERISTICS:
- Age
- Not specified
- Performance status
- Zubrod 0-2
- Life expectancy
- Not specified
- Hematopoietic
- Not specified
- Hepatic
- Not specified
- Renal
- Not specified
- Cardiovascular
- No acute EKG changes, arrhythmia, or other cardiac abnormality that would preclude study participation
- No uncontrolled cardiac disease
- No recent myocardial infarction
- Pulmonary
- Any FEV\_1 level by pulmonary function testing
- Other
- Willing to participate in 12-week long exercise program
- Chemotherapy-induced neuropathy ≤ grade 2
- No uncontrolled diabetes mellitus
- No other medical condition that would preclude study participation
- PRIOR CONCURRENT THERAPY:
- Biologic therapy
- Not specified
- Chemotherapy
- See Disease Characteristics
- Endocrine therapy
- Not specified
- Radiotherapy
- See Disease Characteristics
- Surgery
- Not specified
Exclusion
Key Trial Info
Start Date :
September 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2008
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT00090961
Start Date
September 1 2004
End Date
October 1 2008
Last Update
November 1 2012
Active Locations (60)
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1
Poudre Valley Hospital
Fort Collins, Colorado, United States, 80524
2
Decatur Memorial Hospital Cancer Care Institute
Decatur, Illinois, United States, 62526
3
Cardinal Bernardin Cancer Center at Loyola University Medical Center
Maywood, Illinois, United States, 60153
4
Regional Cancer Center at Memorial Medical Center
Springfield, Illinois, United States, 62781-0001