Status:
COMPLETED
Genetic and Environmental Characteristics of Primary Pulmonary Hypertension
Lead Sponsor:
Vanderbilt University
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Lung Diseases
Hypertension, Pulmonary
Eligibility:
All Genders
Up to 100 years
Brief Summary
The goal of this study is to identify the modifying genes and environmental features that regulate the clinical expression of mutations in bone morphogenetic protein receptor 2 (BMPR2); to develop the...
Detailed Description
BACKGROUND: PPH is a progressive disease that causes obstruction of the smallest arteries in the lungs, which often leads to heart failure. It threatens the lives of thousands of individuals. PPH aff...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Diagnosis of PPH, or family members of individuals diagnosed with PPH, for inclusion in the database and specimen bank
Exclusion
Key Trial Info
Start Date :
August 1 2003
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2009
Estimated Enrollment :
3000 Patients enrolled
Trial Details
Trial ID
NCT00091546
Start Date
August 1 2003
End Date
July 1 2009
Last Update
February 2 2016
Active Locations (1)
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1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232-2650