Status:
RECRUITING
A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Eosinophilia
Hypereosinophilic Syndrome
Eligibility:
All Genders
1-100 years
Brief Summary
Eosinophils are a type of white blood cell. Elevated eosinophil levels can damage the heart, nerves, and other organs, in the syndrome known as hypereosinophilic syndrome (HES). Some individuals have ...
Detailed Description
Study Description: Affected and unaffected members of families with familial hypereosinophilia (FE) will be enrolled and evaluated on this protocol. For affected family members, a thorough clinical e...
Eligibility Criteria
- INCLUSION CRITERIA:
In order to be eligible to participate in this study, an individual must meet all of the following criteria:
- Stated willingness to comply with all study procedures and availability for the duration of the study
- Male or female, aged 1-100 years of age
- Genetically related member of a previously identified family with FE
- Ability of subject to understand and the willingness to sign a written informed consent document.
EXCLUSION CRITERIA:
An individual who meets any of the following criteria will be excluded from participation in this study:
- Any condition that the investigator feels put the subject at unacceptable risk for participation in the study
- Pregnancy (in family members who do not have eosinophilia)
Key Trial Info
Start Date :
June 8 2005
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00091871
Start Date
June 8 2005
Last Update
April 8 2026
Active Locations (1)
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1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892