Status:

COMPLETED

Study Of SU011248 In Patients With Metastatic Non-Small Cell Lung Cancer

Lead Sponsor:

Pfizer

Conditions:

Carcinoma, Non-Small-Cell Lung

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The purpose of this study is to test whether SU011248 has activity and is safe in patients with metastatic non-small cell lung cancer (NSCLC) who have failed a platinum-containing regimen and docetaxe...

Eligibility Criteria

Inclusion

  • Histologically confirmed advanced or metastatic Non-Small Cell Lung Cancer that cannot be cured with surgery, radiation, or combination thereof
  • No more than 2 prior chemotherapy treatments including treatment with a platinum containing therapy
  • Evidence of measurable disease by radiographic technique
  • Male or Female, 18 years or older
  • ECOG performance status of 0 or 1
  • Resolution of all acute toxicities of prior therapies
  • Adequate organ function

Exclusion

  • Major surgery or radiation therapy within 4 weeks
  • Severe hemorrhage within 4 weeks
  • Previous treatment with anti-angiogenesis agents
  • Diagnosis of second malignancy within last five 5 years
  • History of or known brain metastases, spinal cord compression, or carcinomatous meningitis
  • Known HIV
  • Serious acute or chronic illness
  • Current treatment on another clinical trial
  • Pregnant or breastfeeding

Key Trial Info

Start Date :

January 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2007

Estimated Enrollment :

111 Patients enrolled

Trial Details

Trial ID

NCT00092001

Start Date

January 1 2005

End Date

March 1 2007

Last Update

October 16 2008

Active Locations (14)

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Page 1 of 4 (14 locations)

1

Pfizer Investigational Site

Baltimore, Maryland, United States, 21231-1000

2

Pfizer Investigational Site

City of Saint Peters, Missouri, United States, 63376

3

Pfizer Investigational Site

St Louis, Missouri, United States, 63110-1094

4

Pfizer Investigational Site

St Louis, Missouri, United States, 63110