Status:

COMPLETED

Study of the Anti-angiogenesis Agent AG-013736 in Patients With Metastatic Thyroid Cancer

Lead Sponsor:

Pfizer

Conditions:

Thyroid Neoplasms

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This is a Phase 2 study being conducted at multiple centers in the United States. Patients having thyroid cancer that has spread to other parts of the body (i.e., metastatic) are eligible to participa...

Eligibility Criteria

Inclusion

  • Histologically documented thyroid cancer with metastases.
  • Failure of radioactive iodine (131I) to control the disease or radioactive iodine (131I) is not an appropriate therapy (e.g. due to lack of iodine uptake by the tumor)

Exclusion

  • Central lung lesions involving major blood vessels (arteries or veins).(Central lesions that maintain the structural integrity of vessels have the potential to bleed if the tumor lesion undergoes necrosis. MRI or CT angiography should be used in any case where there is any question as to whether blood vessels are involved.)
  • Patients with a history of hemoptysis

Key Trial Info

Start Date :

September 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2009

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT00094055

Start Date

September 1 2004

End Date

January 1 2009

Last Update

June 26 2012

Active Locations (9)

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Page 1 of 3 (9 locations)

1

Pfizer Investigational Site

Santa Monica, California, United States, 90404

2

Pfizer Investigational Site

Aurora, Colorado, United States, 80010

3

Pfizer Investigational Site

Denver, Colorado, United States, 80220

4

Pfizer Investigational Site

Chicago, Illinois, United States, 60637