Status:
COMPLETED
Brain Activities Associated With Different Facial Expressions Using Blood Oxygenation Level Dependent Functional MRI
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Healthy
Eligibility:
All Genders
18+ years
Brief Summary
Objectives: The purpose of this study is to identify areas of brain activation during the urge to yawn. Little is known about how yawning is suppressed, or why yawning often occurs in response to seei...
Detailed Description
Purpose of this study This study will look at how perception and observation of various facial expressions may affect the way different areas of the brain function. We hope to gain a greater understa...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Subjects age 18 and older.
- Subjects willing to abstain from caffeine or alcohol for 48 hours prior to the fMRI scanning.
- EXCLUSION CRITERIA:
- Subjects with any abnormal findings on neurological exam.
- Subjects with a positive urine pregnancy test.
- Subjects who are pregnant.
- Subjects with any finding on the MRI safety questionnaire which prevents them from safely undergoing an MRI scan.
- Subjects with any history of brain tumor, stroke, head trauma or a vascular malformation as obtained by history or from imaging studies.
- Subjects with any history of a severe medical condition, such as cardiovascular disease, which would prevent them from lying flat for up to 60 minutes.
- Subjects without the capacity to give informed consent.
- Subjects with claustrophobia or other restrictions which prevent them from undergoing a scan in a confined space for up to 60 minutes.
Exclusion
Key Trial Info
Start Date :
November 9 2004
Trial Type :
OBSERVATIONAL
End Date :
August 20 2008
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT00096564
Start Date
November 9 2004
End Date
August 20 2008
Last Update
July 2 2017
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892