Status:

COMPLETED

Safety & Efficacy of Certican in Pediatric de Novo Renal Transplant Patients

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

Kidney Transplantation

Eligibility:

All Genders

1-16 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate the safety and tolerability of RAD001 (Certican) administered to pediatric renal transplant recipients, and to provide additional safety data.

Eligibility Criteria

Inclusion

  • Male and female patients no more than 16 years of age.
  • Patients receiving a primary cadaveric or non-HLA identical living donor (related or unrelated) renal transplant.
  • The graft must be functional within 48 hours post transplantation.

Exclusion

  • Cold ischemia time greater than 40 hours.
  • Patients who are recipients of multiple solid organ transplants, including dual and en bloc kidneys, or who have previously received transplanted organs.
  • Patients with panel reactive T cell antibodies of 50 % or higher at the last assessment before transplantation.

Key Trial Info

Start Date :

June 1 2000

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2007

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT00098241

Start Date

June 1 2000

End Date

March 1 2007

Last Update

February 23 2017

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Columbus Children's Hospital

Columbus, Ohio, United States, 43205-2696

2

Dienst Pediatrie UZ Gasthuisberg, Herestraat 49

Leuven, Belgium, 3000