Status:
COMPLETED
Metabolic Syndrome, Inflammation, and Risk of Cognitive Decline
Lead Sponsor:
National Institute on Aging (NIA)
Collaborating Sponsors:
Paul Beeson Faculty Scholars Program
University of California, San Francisco
Conditions:
Cognitive Decline
Eligibility:
All Genders
70-79 years
Brief Summary
The purpose of this study is to determine if the metabolic syndrome is a risk factor for cognitive decline and if this association is modified by inflammation.
Detailed Description
The metabolic syndrome is a clustering of several commonly occurring disorders that include abdominal obesity, high triglycerides, low HDL cholesterol, high blood pressure, and insulin resistance. Thi...
Eligibility Criteria
Inclusion
- Aged 70 to 79
- White or Black
- Community-dwelling in Memphis, TN or Pittsburgh, PA vicinity
- Well-functioning (no difficulty in walking a quarter of a mile or going up 10 steps without resting)
Exclusion
- Any difficulty with activities of daily living
- Clinical dementia
- Inability to communicate with interviewer
- Intention of moving out of vicinity in the next year
- Active treatment for cancer in the previous 3 years
- Participation in a trial involving a lifestyle intervention
Key Trial Info
Start Date :
January 1 1997
Trial Type :
OBSERVATIONAL
End Date :
December 1 2002
Estimated Enrollment :
2632 Patients enrolled
Trial Details
Trial ID
NCT00099567
Start Date
January 1 1997
End Date
December 1 2002
Last Update
November 1 2005
Active Locations (2)
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1
Pittsburgh, Pennsylvania, United States
2
Memphis, Tennessee, United States