Status:
COMPLETED
Hyporeactivity and Gulf War Illness
Lead Sponsor:
US Department of Veterans Affairs
Conditions:
Gulf War Syndrome
Chronic Fatigue Syndrome
Eligibility:
All Genders
Phase:
NA
Brief Summary
This research project is a follow-up to the prior VA-funded study that found that chronic fatigue reported by many Gulf War veterans may be a symptom of dysfunctional cardiovascular stress response re...
Detailed Description
Objective: Our previous VA-funded study found that chronic fatigue reported by some Gulf War veterans may be a symptom of dysfunctional cardiovascular stress response regulation. Specifically, ill vet...
Eligibility Criteria
Inclusion
- All former military personnel who participated in the Gulf War campaign and who meet the criteria for inclusion will be eligible to participate in the study.
- Subjects with medical conditions that could explain their symptoms or with CDC-defined psychiatric exclusions (schizophrenia, mania, bulimia, and substance abuse disorders) will not participate in the study.
- Other exclusions will be pregnancy, traumatic brain injury, or a history of any form of cardiovascular disease or related symptoms.
- Other restrictions on participation will include any medication that impact on cardiovascular autonomic control, benzodiazepines, and antibiotics.
- Subjects taking nonsteroidal anti-inflammatory/analgesic agents, mild short-acting hypnotics, and SSRIs will be accepted into the study, but will be requested to withdraw from their medications with the agreement and under the supervision of their physician. These subjects will be scheduled for the study after a washout period of 5 half-lives.
Exclusion
Key Trial Info
Start Date :
October 1 1999
Trial Type :
INTERVENTIONAL
End Date :
September 1 2002
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00100412
Start Date
October 1 1999
End Date
September 1 2002
Last Update
January 21 2009
Active Locations (1)
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1
Gulf War Research Center
East Orange, New Jersey, United States, 07018