Status:
COMPLETED
Sputum Cytology in Screening Heavy Smokers For Lung Cancer
Lead Sponsor:
University of Colorado, Denver
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Lung Cancer
Eligibility:
All Genders
25+ years
Phase:
PHASE2
Brief Summary
RATIONALE: Screening tests, such as sputum cytology, may help doctors find tumor cells early and plan better treatment for lung cancer. PURPOSE: This phase II trial is studying how well sputum cytolo...
Detailed Description
OBJECTIVES: Primary * Classify annual sputum samples cytologically in participants with or without airflow obstruction and a heavy smoking history. * Correlate sputum cytological atypia (moderate at...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Current or ex-smoker with a lifetime history of cigarette smoking of ≥ 20 pack years, meeting 1 of the following criteria:
- Airflow obstruction
- FEV\_1 \< 75% predicted for age by spirometry
- FEV\_1/FVC ≤ 75% by spirometry
- No airflow obstruction
- No history of lung cancer
- PATIENT CHARACTERISTICS:
- Age
- 25 and over
- Performance status
- Not specified
- Life expectancy
- More than 5 years
- Hematopoietic
- Not specified
- Hepatic
- Not specified
- Renal
- Not specified
- Other
- No cancer within the past 5 years except nonmelanoma skin cancer
- PRIOR CONCURRENT THERAPY:
- Biologic therapy
- Not specified
- Chemotherapy
- Not specified
- Endocrine therapy
- Not specified
- Radiotherapy
- Not specified
- Surgery
- Not specified
Exclusion
Key Trial Info
Start Date :
February 1 1993
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 1994
Estimated Enrollment :
3270 Patients enrolled
Trial Details
Trial ID
NCT00103363
Start Date
February 1 1993
End Date
February 1 1994
Last Update
May 7 2014
Active Locations (1)
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1
University of Colorado Health Sciences Center - Denver
Denver, Colorado, United States, 80262