Status:

COMPLETED

Evaluation of Clinical and Microbial Efficacy and Safety of AzaSite Compared to Tobramycin for Bacterial Conjunctivitis (C-01-401-004)

Lead Sponsor:

Merck Sharp & Dohme LLC

Conditions:

Bacterial Conjunctivitis

Eligibility:

All Genders

1+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate the clinical and microbial efficacy and safety of AzaSite compared to tobramycin for bacterial conjunctivitis. Adults and children one year of age and older wi...

Eligibility Criteria

Inclusion

  • Male or female subject, of any race, who is at least 1 year of age.
  • Subjects must have a clinical diagnosis of acute bacterial conjunctivitis and exhibit mucopurulent or purulent conjunctival discharge (crusty or sticky eyelids, globular and yellow discharge) and redness in at least one eye.
  • The symptoms of bacterial conjunctivitis must be present for 3 days (approximately 72 hours) or less.
  • Must be willing to discontinue contact lens wear for the duration of the study.

Exclusion

  • Any uncontrolled systemic disease or debilitating disease.
  • Use of topical ophthalmic solutions including tear substitutes within 2 hours before and during the study.
  • Use of any topical ophthalmic anti-inflammatory agents within 48 hours before and during study.
  • Any active upper respiratory tract infection.
  • Pregnant or nursing females.
  • Use of any antibiotic (topical or systemic) within 72 hours of enrollment.

Key Trial Info

Start Date :

July 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2005

Estimated Enrollment :

743 Patients enrolled

Trial Details

Trial ID

NCT00105469

Start Date

July 1 2004

End Date

October 1 2005

Last Update

December 16 2013

Active Locations (26)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 7 (26 locations)

1

Renaissance Center

Birmingham, Alabama, United States, 35205

2

Children's Eye Physicians

Littleton, Colorado, United States, 80122

3

Palm Beach Eye Associates

Atlantis, Florida, United States, 33462

4

The Eye Associates

Bradenton, Florida, United States, 34209