Status:
COMPLETED
Effect of a High Protein Diet on the 24-hour Profile of Ghrelin, GH (Growth Hormone) and IGF-1 (Insulin-like Growth Factor-1)
Lead Sponsor:
US Department of Veterans Affairs
Conditions:
Diabetes Mellitus, Type 2
Eligibility:
All Genders
55-75 years
Phase:
NA
Brief Summary
In this study we tested the hypothesis that an increase in protein content of the diet will result in an increase in the 24-hour integrated circulating growth hormone (GH) and insulin-like growth fact...
Detailed Description
Subjects with untreated type 2 diabetes were studied using a randomized crossover design. The study began with an initial two-week observation period. Subjects then were randomly assigned to one arm o...
Eligibility Criteria
Inclusion
- People ages 55 - 75 years old with type 2 diabetes, not receiving oral hypoglycemic agents or insulin.
- Fasting plasma glucose \< 250 mg/dl (\<14 mM) (tGHb \< 14%).
Exclusion
- Subjects will be screened for hematological abnormalities, liver disease, kidney disease, macroalbuminuria (\>300 mg/24 hours), untreated thyroid disease, congestive heart failure, angina, life-threatening malignancies, proliferative retinopathy, diabetic neuropathy, peripheral vascular disease, serious psychological disorders, a body mass index \> 35, and a fasting triglyceride of \> 400 mg/dl.
- Presence of any of the above will be considered exclusion criteria.
Key Trial Info
Start Date :
July 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2009
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT00108225
Start Date
July 1 2004
End Date
May 1 2009
Last Update
July 1 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
VA Medical Center, Minneapolis
Minneapolis, Minnesota, United States, 55417