Status:
WITHDRAWN
Sleep Apnea: Mechanism and Cerebrovascular Consequences
Lead Sponsor:
US Department of Veterans Affairs
Conditions:
Sleep Apnea, Obstructive
Stroke
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
This study will determine the effect of ventilatory stimulation on obstructive sleep apnea in selected patients with stroke. We will select a subset of patients with stroke in the prior 3 months who a...
Detailed Description
This study never enrolled patients. It was a component of a larger VA Merit grant and the other aims of the grant were completed but due to logistic issues and recruitment challenges this particular p...
Eligibility Criteria
Inclusion
- We will select non-obese patients (body mass index \[BMI\] \<30 kg/m2) with stroke diagnosed during the 3 previous months and obstructive sleep apnea on screening sleep study (apnea-hypopnea index \[AHI\] \>15 events/hr of study time).
- Patients with stroke will be selected based on the following criteria: 85 years old or less with a history of ischemic stroke within 3 months resulting in mild to moderate neurological impairment (Rankin scale \< 3)
Exclusion
- Hemorrhagic stroke,
- A history of chronic obstructive lung disease,
- Left ventricular ejection fraction (LVEF) \<55%
- Evidence of nasal or pharyngeal obstruction on physical examination.
Key Trial Info
Start Date :
May 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2007
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00108602
Start Date
May 1 2007
End Date
May 1 2007
Last Update
June 26 2015
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