Status:
UNKNOWN
The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure
Lead Sponsor:
Ejaz, Abulate A, MD
Conditions:
Cardiovascular Disease
Acute Renal Failure
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of this trial is to study the use of nesiritide in thoracic aneurysm repair to prevent acute renal failure. The study hypothesis: Nesiritide, given prophylactically prior to surgery may p...
Detailed Description
Acute renal failure is a major and serious complication of more than 200,000 cardiovascular surgeries performed on adult Americans annually (www.sts.org). The incidence of acute renal failure (ARF) af...
Eligibility Criteria
Inclusion
- Age 18 years or older
- Undergoing thoracic aortic aneurysm surgery
- Impaired renal function
Exclusion
- Prior history of allergy/adverse reaction to Nesiritide
- History of any organ transplant
- Preoperative intra-aortic balloon pump (IABP)
- Decompensated congestive heart failure (CHF)
Key Trial Info
Start Date :
March 1 2005
Trial Type :
INTERVENTIONAL
End Date :
December 1 2007
Estimated Enrollment :
124 Patients enrolled
Trial Details
Trial ID
NCT00110201
Start Date
March 1 2005
End Date
December 1 2007
Last Update
June 24 2005
Active Locations (1)
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1
Shands Hospital at the University of Florida
Gainesville, Florida, United States, 32610