Status:
COMPLETED
Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury
Lead Sponsor:
University of Washington
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Respiratory Distress Syndrome, Adult
Head Injuries, Closed
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the clinical outcome of patients following blunt traumatic injury with hypovolemic shock, who receive either lactated ringer's solution or hypertonic saline wi...
Detailed Description
BACKGROUND: Trauma is the leading cause of death among Americans between the ages of 1 and 35 years. The majority of these deaths result from hypovolemic shock, a type of shock in which the heart is ...
Eligibility Criteria
Inclusion
- Recent blunt trauma
- Of adult size if age is unknown
- Pre-hospital systolic bloood pressure 90 mm Hg or less
- Altered mental status
- Transported directly to Harborview Medical Center from the injury event
Exclusion
- Ongoing CPR
- Transferred from outside hospitals
- Pregnant or suspected pregnancy
- Presence of injuries from penetrating trauma
- Receiving more than 2000 cc of crystaloid prior to study fluid administration
Key Trial Info
Start Date :
April 1 2003
Trial Type :
INTERVENTIONAL
End Date :
March 1 2007
Estimated Enrollment :
209 Patients enrolled
Trial Details
Trial ID
NCT00113685
Start Date
April 1 2003
End Date
March 1 2007
Last Update
May 3 2021
Active Locations (1)
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1
University of Washington
Seattle, Washington, United States, 98104-2499