Status:

COMPLETED

Study of Belatacept in Subjects Who Are Undergoing a Renal Transplant

Lead Sponsor:

Bristol-Myers Squibb

Conditions:

Renal Transplantation

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this trial is to learn if Belatacept is effective and safe as a first line of immunosuppression treatment in patients undergoing a renal transplant where the donor kidney is obtained in...

Eligibility Criteria

Inclusion

  • Subject is a first-time recipient of a kidney transplant from a deceased donor.
  • Specific donor criteria

Exclusion

  • Donor age \<10 years
  • Subjects receiving a concurrent solid organ or cell transplant (lung, heart, etc.)
  • Subjects with a positive T-cell lymphocytotoxic crossmatch.
  • Subjects who are positive for Hepatitis B or C, or HIV
  • Active tuberculosis
  • History of cancer in the last 5 years
  • History of substance abuse
  • Specific laboratory results are exclusionary
  • Mammography suspicious for cancer
  • Allergy to iodine
  • For Long-term extension study-Subjects who have completed three years of study treatment (through Week 156)

Key Trial Info

Start Date :

February 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2014

Estimated Enrollment :

595 Patients enrolled

Trial Details

Trial ID

NCT00114777

Start Date

February 1 2005

End Date

September 1 2014

Last Update

July 7 2017

Active Locations (79)

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Page 1 of 20 (79 locations)

1

University Of Alabama At Birmingham

Birmingham, Alabama, United States, 35294

2

Ucla Kidney & Kidney-Pancreas Transplant Research Office

Los Angeles, California, United States, 90024

3

National Institute Of Transplantation

Los Angeles, California, United States, 90057

4

Sharp Memorial Hospital

San Diego, California, United States, 92133