Status:
COMPLETED
A Study of Neurophysiologic Changes in Individuals With Parkinson's Disease
Lead Sponsor:
Institute for Neurodegenerative Disorders
Collaborating Sponsors:
Molecular NeuroImaging
Conditions:
Parkinson's Disease
Parkinsonian Syndrome
Eligibility:
All Genders
22+ years
Brief Summary
The goal of this study is to investigate neurophysiologic tests that have the potential of serving as screening tools for Parkinson's disease. These neurophysiologic tests will be administered to indi...
Detailed Description
One of the greatest challenges in Parkinson's research is the identification of individuals who are at risk or have early Parkinson's disease (PD) or parkinsonian syndrome (PS). Subtle signs that do n...
Eligibility Criteria
Inclusion
- As a participant with PD or PS:
- Age \>21
- Clinical diagnosis of PD or PS (at least two of the three cardinal symptoms: resting tremor, rigidity, bradykinesia) and a clinical response to dopaminergic therapy
- For Healthy Control:
- Age \>21
Exclusion
- As a participant with PD or PS:
- Any other concomitant neurologic condition likely to interfere with handwriting, use of the computer, or other motor tasks tested in this study (e.g. stroke, demyelinating disease, visual loss)
- For Healthy Control:
- Any indication of parkinsonism on examination
- Any other concomitant neurologic condition likely to interfere with handwriting, use of the computer, or other motor tasks (e.g. stroke, demyelinating disease, visual loss)
Key Trial Info
Start Date :
May 1 2003
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2012
Estimated Enrollment :
620 Patients enrolled
Trial Details
Trial ID
NCT00117195
Start Date
May 1 2003
End Date
January 1 2012
Last Update
February 9 2012
Active Locations (1)
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1
Institute for Neurodegenerative Disorders
New Haven, Connecticut, United States, 06510