Status:

COMPLETED

A Study of Repeat-Dose Subcutaneous Darbepoetin Alfa in Subjects With Congestive Heart Failure and Anemia, and a Single Dose in Healthy Age- and Sex-Matched Control Subjects

Lead Sponsor:

Amgen

Conditions:

Anemia

Congestive Heart Failure

Eligibility:

All Genders

18+ years

Phase:

PHASE1

PHASE2

Brief Summary

The purpose of this study is to evaluate the single dose pharmacokinetics (PK) of subcutaneous (SC) darbepoetin alfa in subjects with congestive heart failure (CHF) and anemia.

Eligibility Criteria

Inclusion

  • Inclusion Criteria: - Symptomatic CHF despite optimized therapy for at least the previous 3 months (treatment included a diuretic, angiotensin converting enzyme \[ACE\] inhibitor, and/or an A2 antagonist, unless not tolerated) - Hemoglobin greater than or equal to 12.5 g/dL at the time of screening

Exclusion

    Key Trial Info

    Start Date :

    June 1 2002

    Trial Type :

    INTERVENTIONAL

    End Date :

    July 1 2004

    Estimated Enrollment :

    Patients enrolled

    Trial Details

    Trial ID

    NCT00117247

    Start Date

    June 1 2002

    End Date

    July 1 2004

    Last Update

    October 16 2009

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