Status:
COMPLETED
Sertraline and Habit Reversal in the Treatment of Patients With Trichotillomania
Lead Sponsor:
Massachusetts General Hospital
Collaborating Sponsors:
Pfizer
Conditions:
Impulse Control Disorders
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to assess the extent of symptom remission in patients with trichotillomania following treatment with sertraline and/or behavior therapy.
Detailed Description
The purpose of this study is to assess the extent of symptom remission in patients with trichotillomania following treatment with sertraline and/or behavior therapy. Following entry into the study, s...
Eligibility Criteria
Inclusion
- Patients will have a DSM-IV diagnosis of TTM.
- TTM symptoms for at least 4 months.
- Scalp as primary site of hair pulling.
- HPS score greater than or equal to 15 OR TTM Impact Scale score greater than 30.
- Written informed consent.
- Men or women aged 18-65 years old.
- Females of childbearing potential must have a negative serum beta-HCG pregnancy test.
Exclusion
- Pregnant women or women of childbearing potential who are not using a medically accepted means of contraception.
- Patients who, in the investigator's judgement, pose a serious suicidal or homicidal risk.
- Serious or unstable medical illness including cardiovascular, hepatic, renal, respiratory, endocrine, neurologic, or hematologic disease. Patients on anticoagulant therapy.
- History of seizure disorder.
- Comorbid bipolar disorder, psychosis, organic mental disorder, or developmental disorder.
- If there is a history of substance abuse, patients must be in remission at least 6 months.
- Past trials of sertraline.
- Currently being treated with behavioral therapy, specifically habit reversal training, for TTM.
- Other medications for medical disorders that may interact with sertraline.
Key Trial Info
Start Date :
January 1 2000
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2004
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT00118014
Start Date
January 1 2000
End Date
August 1 2004
Last Update
May 20 2008
Active Locations (1)
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1
Massachusetts General Hospital - OCD Clinic
Charlestown, Massachusetts, United States, 02129