Status:
COMPLETED
EUS-FNA in the Pre-Operative Evaluation of Patients With Lung Cancer
Lead Sponsor:
University Hospital, Ghent
Conditions:
Lung Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
This trial examines the role of EUS-FNA (Oesophageal Endoscopic Ultrasound with Fine Needle Aspiration) as an endoscopic technique for the mediastinal staging of patients with lung cancer. Patients w...
Eligibility Criteria
Inclusion
- patients with histological or cytological proof of non small cell lung cancer (NSCLC) or with a high clinical suspicion for lung cancer (but without pathologically confirmed diagnosis from the bronchoscopy or CT guided transthoracal biopsies) in whom the next step is normally a diagnostic or therapeutic surgical intervention
- no distant metastases after routine clinical work up (PET is optional, not mandatory)
- provision of a written informed consent
- recent CT-scan of the thorax (\<28 days before randomization date)
- age 18 years or older
- clinically fit for surgery
Exclusion
- proof of small cell lung cancer (SCLC) with CWU (bronchoscopy or CT guided transthoracal punction)
- stage IV NSCLC
- patients with a solitary pulmonary nodule (thus without enlarged mediastinal lymph nodes on CT and without mediastinal PET hot spots) : these do not require further mediastinal investigation
- former therapy (chemotherapy or radiotherapy or surgery) for lung cancer
- other concomitant malignancies
- reasons for which the patient is unable to swallow the EUS-instrument (e.g. zenker diverticulum, unexplained esophageal stenosis)
- uncorrected coagulopathy
Key Trial Info
Start Date :
February 1 2005
Trial Type :
INTERVENTIONAL
End Date :
February 1 2007
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00119470
Start Date
February 1 2005
End Date
February 1 2007
Last Update
December 28 2007
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital Ghent
Ghent, Belgium, 9000