Status:
UNKNOWN
Ketamine Sedation in Mechanically Ventilated Patients
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Respiratory Insufficiency
Pain
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
* Adequate sedation is of paramount importance to avoid stress and pain in mechanically ventilated patients. It is usually achieved by infusing sedatives (benzodiazepine) and analgesic (opiate) drugs....
Detailed Description
* Mechanical ventilation is widely used in critically ill patients. Sedation is used in most instances to alleviate symptoms of pain and distress. It usually consists of an association of opiates and ...
Eligibility Criteria
Inclusion
- Mechanically ventilated patients who receive adequate dosing of sedative agents (midazolam \> 0.15 mg/kg/h plus sufentanil \> 0.3 mcg/kg/h)
- Persistence of agitation indicating that sedation is not appropriate, as assessed by validated sedation scales (Harris scare; Motor Activity Assessment scale).
Exclusion
- Pregnancy
- Patient who already receives neuromuscular blocking agents
Key Trial Info
Start Date :
December 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2007
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00122759
Start Date
December 1 2005
End Date
September 1 2007
Last Update
July 23 2007
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Service de Réanimation Médicale, Hôpital Louis Mourier
Colombes, France, 92700