Status:
COMPLETED
Effects of Garlic Supplements on Drug Metabolism
Lead Sponsor:
Fred Hutchinson Cancer Center
Collaborating Sponsors:
National Center for Complementary and Integrative Health (NCCIH)
Conditions:
Healthy
Eligibility:
All Genders
18-45 years
Brief Summary
This study will determine whether garlic supplements affect the way certain drugs are processed in the body.
Detailed Description
Garlic supplements, which are often used to lower cholesterol and prevent cancer, are one of the most commonly used herbal products in the United States. However, little is known about the way garlic...
Eligibility Criteria
Inclusion
- Body mass index (BMI) between 20 and 32
- Able to read and understand English
- MUST LIVE WITHIN THE SEATTLE, WA AREA.
Exclusion
- Current use of herbal medicines other than oral contraceptives
- History of cardiopulmonary, liver, renal or endocrine disease
- Allergy or sensitivity to any of the drugs that will be used in the probe cocktails or the garlic supplements
- Daily consumption of vegetables with a high allium content, including garlic, shallots, leeks, and chives
- Pregnancy or breastfeeding
Key Trial Info
Start Date :
July 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2009
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00122889
Start Date
July 1 2005
End Date
March 1 2009
Last Update
January 1 2010
Active Locations (1)
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1
Fred Hutchinson Cancer Research Center
Seattle, Washington, United States, 98109