Status:

UNKNOWN

Buprenorphine and Integrated HIV Care Evaluation

Lead Sponsor:

The New York Academy of Medicine

Collaborating Sponsors:

Health Resources and Services Administration (HRSA)

El Rio Santa Cruz Neighborhood Health Center

Conditions:

Opioid-Related Disorders

HIV Infections

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to assess the feasibility, cost and effectiveness of interventions designed to integrate buprenorphine treatment for opioid dependence into HIV primary care in ten HIV car...

Detailed Description

Programs that integrate medical care and drug treatment have shown great promise in improving health and substance use related outcomes. The overlap in the epidemics of HIV (with its complex medical n...

Eligibility Criteria

Inclusion

  • HIV-infected
  • Clinical diagnosis of opioid dependence
  • Fluent in English or Spanish
  • 18 years or older

Exclusion

  • Liver function tests (transaminase only) at five times or higher than normal level;
  • Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (DSM-IV) criteria for benzodiazepine abuse or dependence within the past 6 months;
  • DSM-IV criteria for alcohol dependence within the past 6 months;
  • Actively suicidal;
  • Psychiatric impairment that impedes ability to consent (dementia, delusional, actively psychotic);
  • Methadone dose exceeding levels allowing for safe transition to buprenorphine;
  • Pregnant women and women actively trying to become pregnant;
  • Clinical judgment of local site principal investigator that patient is inappropriate

Key Trial Info

Start Date :

August 1 2005

Trial Type :

INTERVENTIONAL

End Date :

December 1 2008

Estimated Enrollment :

1350 Patients enrolled

Trial Details

Trial ID

NCT00124358

Start Date

August 1 2005

End Date

December 1 2008

Last Update

March 27 2007

Active Locations (10)

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Page 1 of 3 (10 locations)

1

El Rio Santa Cruz Neighborhood Health Center

Tucson, Arizona, United States, 85745

2

Organization to Achieve Solutions in Substance Abuse

Oakland, California, United States, 94612

3

University of California San Francisco

San Francisco, California, United States, 94110

4

Yale University School of Medicine AIDS Program

New Haven, Connecticut, United States, 06510