Status:

COMPLETED

Atorvastatin and Endothelial Function in Type 2 Diabetes Mellitus (ATTEND-Study)

Lead Sponsor:

University of Southern Denmark

Collaborating Sponsors:

Pfizer

Conditions:

Type 2 Diabetes Mellitus

Eligibility:

All Genders

Phase:

PHASE4

Brief Summary

The aim of this study is to examine the effect of intensive cholesterol lowering therapy and tight blood pressure (BP) regulation on endothelial function (inner cell layer of vessels that determines d...

Detailed Description

Background:The prevalence of diagnosed type 2 diabetes mellitus (DM) is estimated to 2-4% in the general population in most European countries. DM is associated with an increased frequency of manifest...

Eligibility Criteria

Inclusion

  • Type 2 diabetes mellitus,
  • Total cholesterol \<6.5 mmol/l
  • Signed informed consent

Exclusion

  • Documented CAD or peripheral vascular disease
  • Treatment with lipid-lowering drugs
  • Contraindications to HMG-CoA reductase therapy
  • Potential noncompliance

Key Trial Info

Start Date :

July 1 2001

Trial Type :

INTERVENTIONAL

End Date :

December 1 2004

Estimated Enrollment :

186 Patients enrolled

Trial Details

Trial ID

NCT00124397

Start Date

July 1 2001

End Date

December 1 2004

Last Update

August 5 2005

Active Locations (1)

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1

Department of Medical Research

SHF Svendborg, Svendborg, Denmark, 5700