Status:

COMPLETED

SELESTIAL: Trial of Insulin to Control Blood Sugar After Acute Stroke Using Magnetic Resonance Imaging (MRI) End-Points

Lead Sponsor:

University of Glasgow

Collaborating Sponsors:

South Glasgow University Hospitals NHS Trust

The Stroke Association, United Kingdom

Conditions:

Acute Stroke

Hyperglycemia

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

High blood sugar (hyperglycaemia) affects 40% of acute stroke patients and has a major adverse effect on survival and recovery. Increased production of lactic acid in brain tissue that has a poor bloo...

Detailed Description

Hyperglycaemia is present in 40-60% of patients with acute ischaemic stroke and adversely affects survival and outcome. This effect is independent of stroke severity or pathology, and is most striking...

Eligibility Criteria

Inclusion

  • Acute stroke within 24h of onset
  • Lesion on acute diffusion weighted MRI
  • \>18 years age

Exclusion

  • Coma
  • Major concomitant illness limiting survival

Key Trial Info

Start Date :

May 1 2004

Trial Type :

INTERVENTIONAL

End Date :

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT00124826

Start Date

May 1 2004

Last Update

February 1 2006

Active Locations (1)

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Institute of Neurological Sciences

Glasgow, United Kingdom, G51 4TF