Status:
COMPLETED
Comparison of Two Treatments for Post-Traumatic Stress Disorder
Lead Sponsor:
Case Western Reserve University
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Post-Traumatic Stress Disorder
Eligibility:
All Genders
18-65 years
Phase:
PHASE3
Brief Summary
This study will compare the short- and long-term effectiveness of two different treatments for people with post-traumatic stress disorder.
Detailed Description
Exposure to traumatic events, such as automobile accidents and assault, can cause individuals to develop persistent psychological difficulties such as post-traumatic stress disorder (PTSD). PTSD is an...
Eligibility Criteria
Inclusion
- DSM-IV diagnosis of PTSD
- Experienced traumatic event at least 12 weeks prior to study entry
- Willingness to discontinue current CBT or antidepressant treatment
Exclusion
- Current diagnosis of schizophrenia or delusional disorder
- Medically unstable bipolar disorder, depression with psychotic features, or depression requiring psychiatric treatment
- Current diagnosis of alcohol or substance dependence within 3 months prior to study entry
- Ongoing intimate relationship with the perpetrator of the traumatic event
- History of nonresponse to either CBT or sertraline
- Medical contraindication for sertraline
Key Trial Info
Start Date :
September 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2011
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00127673
Start Date
September 1 2004
End Date
August 1 2011
Last Update
May 24 2022
Active Locations (1)
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1
Department of Psychology, University of Washington
Seattle, Washington, United States, 98195