Status:
COMPLETED
Prevention of Atrial Fibrillation Following Noncardiac Thoracic Surgery
Lead Sponsor:
Indiana University
Collaborating Sponsors:
Purdue University
Conditions:
Atrial Fibrillation
Eligibility:
All Genders
40+ years
Phase:
PHASE4
Brief Summary
The investigators hypothesize that the medication amiodarone decreases the incidence of atrial fibrillation (AF) following non-cardiac open-chest surgery. Their specific aims are to: * Determine the ...
Detailed Description
Thousands of patients undergo major non-cardiac open-chest surgery in the United States each year. These surgeries most often consist of lung surgery, in which one lobe of the lung is removed (lobecto...
Eligibility Criteria
Inclusion
- Males or females over the age of 40
- Scheduled to undergo pneumonectomy or lobectomy
Exclusion
- History (hx) of atrial fibrillation
- Prior severe side effects from amiodarone
- Elevated liver enzymes \>3 times the upper limit of normal (UNL)
- QTc interval \> 450 ms
- Receiving class Ia or class III antiarrhythmics
Key Trial Info
Start Date :
September 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2008
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT00127712
Start Date
September 1 2004
End Date
February 1 2008
Last Update
September 18 2013
Active Locations (1)
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1
Indiana University
Indianapolis, Indiana, United States, 46202