Status:
COMPLETED
Bioavailability of Folate From a Mixed Diet Using a Stable Isotope Method
Lead Sponsor:
Wageningen Centre for Food Sciences
Collaborating Sponsors:
Wageningen University
Conditions:
Folate Bioavailability
Healthy
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The main objectives of this project are: 1. to determine the relative bioavailability of dietary folate from a total diet, compared with synthetic folic acid and 2. to determine the bioavailability w...
Detailed Description
Folate plays a role in the prevention of certain birth defects and possibly also in prevention of neurocognitive diseases, cancer and cardiovascular disease. The proportion of dietary folate that is a...
Eligibility Criteria
Inclusion
- Serum B12 \>118pmol/L;
- Serum creatinine \<125micromol/L;
- Plasma total homocysteine \<26micromol/L.
Exclusion
- Cardiovascular disease, cancer, rheumatoid arthritis, epilepsy, gastro-intestinal disorders;
- Use of drugs interfering with folate metabolism;
- Use of B vitamins within the period three months prior to the study.
- Body Mass Index (BMI) \> 30
Key Trial Info
Start Date :
May 1 2005
Trial Type :
INTERVENTIONAL
End Date :
June 1 2005
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT00130585
Start Date
May 1 2005
End Date
June 1 2005
Last Update
October 4 2005
Active Locations (1)
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1
Wageningen University
Wageningen, Netherlands, 6700EV