Status:
RECRUITING
Establishing a Tumor Bank in Families With Multiple Lymphoproliferative Malignancies
Lead Sponsor:
Dana-Farber Cancer Institute
Conditions:
Non-Hodgkin's Lymphoma
Hodgkin's Disease
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to investigate possible genetic factors that contribute to the development of lymphomas. The databank will be used to determine whether familial lymphomas have unique gene...
Detailed Description
* Patients who participate will be asked to complete detailed family and medical history questionnaires initially, with a follow-up questionnaire every year. * Patients will be asked to supply a blood...
Eligibility Criteria
Inclusion
- Any individual diagnosed with non-Hodgkin's lymphoma or Hodgkin's disease or chronic lymphocytic leukemia (CLL), who has a 1st degree relative (parent, sibling or child) with a lymphoproliferative disorder; or families in which the individual has a lymphoproliferative disorder, and an unusual clustering of frequent or premature solid tumors is also observed.
- Family members of the individual, either affected or unaffected with lymphoma, who are contacted by the individual and agree to participate in the study.
- Deceased family members may be included in the study. Public records such as death certificates may be used to confirm the history. Consent for medical records or tissue blocks will be obtained from the deceased family member's next of kin. The hierarchy of relatives defined as next of kin is spouse, offspring, parents and siblings. Archived tissue samples may be used for genetic research.
- Age \> 18 years
Exclusion
- Subjects without a family history of lymphoma
Key Trial Info
Start Date :
August 9 2004
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2033
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT00131014
Start Date
August 9 2004
End Date
January 1 2033
Last Update
July 22 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02115