Status:

COMPLETED

Long-Term Follow-Up Study of Psoriasis Patients

Lead Sponsor:

MedImmune LLC

Conditions:

Psoriasis

Eligibility:

All Genders

18-65 years

Brief Summary

The purpose of this study is to evaluate the long-term safety and profile of psoriasis patients who have completed participation in a previous study and who received treatment with MEDI-507.

Detailed Description

This study will evaluate the long-term safety and lymphocyte repletion profile of psoriasis patients who have completed participation in a previous study and who received treatment with MEDI-507. Pati...

Eligibility Criteria

Inclusion

  • The patient has previously completed participation (i.e., completed per protocol, including any long term follow-up; or discontinued from the study due to withdrawal of consent, loss to follow-up, or other reason) in a Medimmune, Inc. study of MEDI-507 in psoriasis in which they received MEDI-507 (or placebo for patients who participated in a blinded placebo-controlled study of MEDI-507, and for whom the treatment assignment in that study has not been unblinded at the time of entry into this study)
  • The patient had an absolute lymphocyte count (ALC) \> 30% lower than baseline (defined as baseline prior to any MEDI-507 exposure; or, for patients whose treatment assignments have not been unblinded at the time of entry into this study, drug exposure) at his/her final visit (excluding any long-term follow-up visits) in the most recent Medimmune, Inc. study in which the patient participated; or the patient had an absolute CD4 count of \< 250 cells/uL at his/her final visit (including any protocol-specific long-term follow up) in the most recent Medimmune, Inc. study in which the patient participated.
  • Written informed consent obtained from the patient

Exclusion

  • There are no exclusion criteria.

Key Trial Info

Start Date :

August 1 2002

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2007

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT00131066

Start Date

August 1 2002

End Date

December 1 2007

Last Update

September 22 2008

Active Locations (21)

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Page 1 of 6 (21 locations)

1

Dermatology Research Clinic

Little Rock, Arkansas, United States, 72205

2

Cherry Creek Dermatology

Denver, Colorado, United States, 80246

3

Atlanta Dermatology, Vein & Research Center, LLC

Alpharetta, Georgia, United States, 30005

4

Future Care Studies

Springfield, Massachusetts, United States, 72205