Status:

COMPLETED

Switching Therapy From Lamivudine to Telbivudine Versus Continued Lamivudine in Adults With Chronic Hepatitis B

Lead Sponsor:

Novartis

Collaborating Sponsors:

Novartis Pharmaceuticals

Conditions:

Chronic Hepatitis B

Eligibility:

All Genders

18-70 years

Phase:

PHASE3

Brief Summary

This study is being conducted to compare the safety and effectiveness of switching treatment from lamivudine to telbivudine (LdT) against continued lamivudine treatment. Results from patients who were...

Eligibility Criteria

Inclusion

  • Documented clinical history compatible with chronic hepatitis B
  • Patient has compensated liver disease
  • Patient has received previous treatment with lamivudine for a duration of at least 3 months and not more than 12 months
  • Other protocol-defined inclusion criteria may apply.

Exclusion

  • Patient is pregnant or breastfeeding
  • Patient is co-infected with hepatitis C, hepatitis D or HIV
  • Patient previously received antiviral treatment for hepatitis B other than lamivudine in the preceding 12 months
  • Other protocol-defined exclusion criteria may apply.

Key Trial Info

Start Date :

February 1 2005

Trial Type :

INTERVENTIONAL

End Date :

December 1 2006

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT00132652

Start Date

February 1 2005

End Date

December 1 2006

Last Update

February 23 2017

Active Locations (14)

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Page 1 of 4 (14 locations)

1

San Diego, California, United States

2

New York, New York, United States

3

Philadelphia, Pennsylvania, United States

4

Westmead, Australia