Status:
COMPLETED
Multicenter Uveitis Steroid Treatment (MUST) Trial
Lead Sponsor:
JHSPH Center for Clinical Trials
Collaborating Sponsors:
National Eye Institute (NEI)
Conditions:
Uveitis
Eligibility:
All Genders
13+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to compare the effectiveness of standardized systemic therapy versus fluocinolone acetonide implant therapy for the treatment of severe cases of non-infectious intermediat...
Detailed Description
The MUST trial is a randomized controlled clinical trial comparing two treatments for patients with vision-threatening non-infectious intermediate uveitis, posterior uveitis, or panuveitis: * local t...
Eligibility Criteria
Inclusion
- Age 13 years or older
- Best-corrected visual acuity of hand motions or better in at least one eye with uveitis
- Intraocular pressure 24 mm Hg or less in all eyes with uveitis
Exclusion
- Inadequately controlled diabetes
- Uncontrolled glaucoma
- Advanced glaucomatous optic nerve injury
- A history of scleritis; presence of an ocular toxoplasmosis scar.
- HIV infection or other immunodeficiency disease for which corticosteroid therapy would be contraindicated according to best medical judgment
Key Trial Info
Start Date :
September 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
255 Patients enrolled
Trial Details
Trial ID
NCT00132691
Start Date
September 1 2005
End Date
December 1 2010
Last Update
November 25 2016
Active Locations (23)
Enter a location and click search to find clinical trials sorted by distance.
1
Jacobs Retina Center, UCSD
La Jolla, California, United States, 92037
2
Doheny Eye Institute, USC
Los Angeles, California, United States, 90033
3
Jules Stein Eye Institute, UCLA
Los Angeles, California, United States, 90095
4
Proctor Foundation, UCSF
San Francisco, California, United States, 94143