Status:

COMPLETED

Long-Term Dopamine Transporter Imaging and Clinical Assessment of Parkinson's Disease Progression

Lead Sponsor:

Institute for Neurodegenerative Disorders

Collaborating Sponsors:

United States Department of Defense

Conditions:

Parkinson Disease

Eligibility:

All Genders

22+ years

Phase:

PHASE2

Brief Summary

The purpose of this project is to assess the change in dopamine transporter density in Parkinson's disease subjects during a sixty month period including a nine month treatment trial of levodopa. Dopa...

Detailed Description

All subjects will be imaged at the Institute for Neurodegenerative Disorders. Subjects will be evaluated sequentially with \[123I\]ß-CIT SPECT and standardized clinical rating scales during a sixty m...

Eligibility Criteria

Inclusion

  • Prior participation in the study titled Dopamine Transporter Imaging Assessment of Parkinson's Disease Progression (DAMD17-99-1-9472) \[123I\] B-CIT and Spect in Vivo Imaging Assessment of Dopamine Transporter Density in Subjects With Early Parkinson's Disease Participating in Earlier Vs. Later Levodopa in Parkinson's Disease (ELLDOPA)\].

Exclusion

  • Inability to sign informed consent and participate in all study procedures.
  • Mini mental status exam \< 25.
  • Pregnancy

Key Trial Info

Start Date :

April 1 2000

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2007

Estimated Enrollment :

142 Patients enrolled

Trial Details

Trial ID

NCT00134784

Start Date

April 1 2000

End Date

May 1 2007

Last Update

August 8 2014

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