Status:
TERMINATED
Method of Oxygen Delivery and the Effect on Transcutaneous PaCO2
Lead Sponsor:
The University of Texas Health Science Center, Houston
Conditions:
Lung Diseases, Obstructive
Eligibility:
All Genders
1-6 years
Phase:
PHASE2
PHASE3
Brief Summary
Infants of \< 1500 grams of birth weight who require a \> 1 week mechanical ventilation (breathing machine) or CPAP \[continuous positive airway pressure\] (oxygen at a high flow through the nose) may...
Detailed Description
Specific Question: Among low birth weight infants with a supplemental oxygen requirement, do modifications in the flow (L/min) of nasal cannula gas alter the level of transcutaneous PCO2 in the short...
Eligibility Criteria
Inclusion
- Infants with an oxygen requirement (FiO2 of \> 0.3 to maintain pulse oxygen saturations 85-95%)
- On the ventilator or nasal continuous positive airway pressure (NCPAP) for \> 1 week ready to be changed to nasal cannula
- Weight less than 2500 grams and \< 1500 grams birth weight
Exclusion
- Obvious chromosomal or congenital anomaly for craniofacial or respiratory system anomalies
- Known significant congenital heart disease (excluding patent ductus arteriosus)
- Seizures or known neuromuscular disease
- Received steroids in week prior to eligibility
Key Trial Info
Start Date :
August 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2006
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT00135252
Start Date
August 1 2005
End Date
June 1 2006
Last Update
January 8 2008
Active Locations (1)
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1
Memorial Hermann Children's Hospital
Houston, Texas, United States, 77030