Status:
COMPLETED
Continuous Femoral Nerve Block Following Total Knee Replacement
Lead Sponsor:
National Institute of General Medical Sciences (NIGMS)
Collaborating Sponsors:
Foundation for Anesthesia Education and Research
Arrow International
Conditions:
Pain
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The purpose of this study is to determine if putting local anesthetic-or numbing medication-through a tiny tube next to the nerves that go to the knee will improve pain control during physical therapy...
Detailed Description
What procedures would be done as part of your normal clinical care (even if you did not participate in this research)? You will have some monitors placed (such as a blood-pressure cuff) and be given ...
Eligibility Criteria
Inclusion
- Patients undergoing unilateral, primary total knee arthropathy (TKA)
- 18-80 years of age
- Be able to understand the possible local anesthetic-related complications, study protocol, and care of the catheter and infusion pump system and are already planning on having a perineural catheter placed for postoperative analgesia
Exclusion
- Any contraindication to femoral block/catheter
- Any comorbidity which results in moderate or severe functional limitation (American Society of Anesthesiologists \[ASA\] physical status \>2)
- Baseline oxygen saturation \< 96% on room air
- Known hepatic or renal insufficiency (creatinine level \> 1.5 mg/dL)
- Allergy to study medications (other than nonsteroidal anti-inflammatory agents \[NSAIDs\] and acetaminophen)
- Inability to communicate with the authors
- Morbid obesity (body mass index \[BMI\]\>40 kg/m2)
- History of opioid abuse or chronic regular opioid use (use within the 2 weeks prior to surgery and duration of use \> 4 weeks)
Key Trial Info
Start Date :
January 1 2005
Trial Type :
INTERVENTIONAL
End Date :
July 1 2008
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00135889
Start Date
January 1 2005
End Date
July 1 2008
Last Update
October 8 2009
Active Locations (2)
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1
University of California San Diego
La Jolla, California, United States, 92037
2
University of Florida
Gainesville, Florida, United States, 32610-0254