Status:
COMPLETED
Outpatient Treatment of Alcohol Withdrawal Syndrome
Lead Sponsor:
Hvidovre University Hospital
Conditions:
Alcoholism
Alcohol Withdrawal
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of this study is to compare a fixed-schedule therapy versus a symptom-triggered therapy for alcohol withdrawal syndrome in medical outpatients. Objectives: * Self-governance in monitorin...
Detailed Description
The objective of this study is to compare a fixed-schedule therapy versus a symptom-triggered therapy for alcohol withdrawal syndrome in medical outpatients. Objectives: * Self-governance in monitor...
Eligibility Criteria
Inclusion
- Patients above the age of 18
- Fulfilled informed consent
- Abstained from alcohol within the last 72 hours.
- Agree on both treatment regimens.
- Abstinence during 10 days (monitoring and medication period), i.e. treatment with disulfiram or oral alcometer test on every attendance (Lion Alcometer S-D2).
Exclusion
- Oral alcoholmeter test \> 0.1.
- Treatment of AWS within the last week
- 3 earlier attempts at outpatient detoxification within the last 2 months without success.
- Allergy or adverse reactions to chlordiazepoxide
- Treatment with medication in interaction with chlordiazepoxide
- Psychiatric comorbidity within the last year, dependence on other drugs except nicotine dependence
- Medically severe comorbidity, especially severe liver insufficiency
- Severe cardiovascular diseases, NIDDM and IDDM.
- A history within the last year of seizures and delirium tremens.
- Patients should be cooperative in terms of cooperation and understanding of the Danish language.
- Females of fertile age without safe contraception, (i.e. IUD, hormone tablets or sterilisation) also pregnant or breastfeeding women were excluded.
Key Trial Info
Start Date :
August 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2008
Estimated Enrollment :
165 Patients enrolled
Trial Details
Trial ID
NCT00136617
Start Date
August 1 2003
End Date
September 1 2008
Last Update
March 2 2009
Active Locations (1)
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1
Alcohol Clinics at Hvidovre Hospital
Hvidovre, Denmark, 2650