Status:
TERMINATED
Responses of Premature Infants to Measles-Mumps-Rubella (MMR) and Varicella Vaccines
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Measles
Mumps
Eligibility:
All Genders
Up to 16 years
Brief Summary
The purpose of this study is to see if the MMR and chickenpox vaccines work as well in premature infants as in children that were carried to full term. A group of children who were carried full-term w...
Detailed Description
The purpose of this study is to see if the MMR and chickenpox vaccines work as well in premature infants as in children that were carried to full term. A group of children who were carried full-term w...
Eligibility Criteria
Inclusion
- Premature infant \< 29 weeks gestation at birth or term infant \>= 37 weeks gestation at birth.
- Postnatal age \< 16 months, 0 days.
- Has not yet received MMR or varicella vaccines. (There are no restrictions on the administration of other vaccines at the time of MMR/varicella vaccination.)
- Parental permission.
- Agreement of primary care pediatrician/ health care provider.
- Receives primary pediatric care within an approximate 25-mile radius of the University of Rochester.
- Healthy status at enrollment.
Exclusion
- Known immunodeficiency.
- Systemic corticosteroid therapy at the time of MMR/varicella vaccination.
- Requiring oxygen therapy.
- Clinically significant findings on review of medical history and physical exam determined by the investigator or sub-investigator to be sufficient for exclusion.
- Any condition determined by the investigator that would interfere with the evaluation of the vaccine or be a potential health risk to the subject.
Key Trial Info
Start Date :
June 1 2004
Trial Type :
OBSERVATIONAL
End Date :
June 1 2005
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT00138255
Start Date
June 1 2004
End Date
June 1 2005
Last Update
August 27 2010
Active Locations (1)
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1
University of Rochester School of Medicine and Dentistry
Rochester, New York, United States, 14642