Status:

COMPLETED

A Roentgen Stereophotogrammetric Analysis on Migration of Knee Prostheses.

Lead Sponsor:

University of Aarhus

Collaborating Sponsors:

Aarhus University Hospital

Zimmer Biomet

Conditions:

Osteoarthritis

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

The purpose of this study is to compare the early migration of two uncemented total knee arthroplasties with different metal coating. Only the tibial prosthesis plateau varies. One is made out of tant...

Detailed Description

Around 4% of total knee arthroplasties (TKA) are revised 15 years after the primary operation, most due to loosening of the implant. The use of uncemented prostheses are expected to extend the fixatio...

Eligibility Criteria

Inclusion

  • Patients with one- or double-sided primary knee arthrosis.
  • Patients with a sufficient bone quality for implantation of an uncemented prosthesis.
  • Informed and written patient consent.

Exclusion

  • Patients with neuromuscular or vascular diseases in the affected leg.
  • Patients who peroperatively are estimated unsuitable for an uncemented knee arthroplasty e.g. due to bone cysts or dilution of the bone mass.
  • Patients who use non-steroid anti-inflammatory drugs (NSAID) and cannot refrain from taking them postoperatively (this includes COX-2-inhibitors).
  • Patients with osteoporosis estimated from the preoperative x-ray or former diagnosis of osteoporosis.
  • Patients with fracture sequelae.
  • Women, who are pregnant or are at risk of getting pregnant.

Key Trial Info

Start Date :

November 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2010

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT00138853

Start Date

November 1 2003

End Date

April 1 2010

Last Update

December 19 2022

Active Locations (1)

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Orthopaedic Center, Aarhus University Hospital.

Aarhus, Denmark, 8200