Status:

UNKNOWN

DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome

Lead Sponsor:

Bispebjerg Hospital

Collaborating Sponsors:

H. Lundbeck A/S

Danish Heart Foundation

Conditions:

Depression

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Objective: To evaluate the efficacy of preventive treatment with a selective serotonin reuptake inhibitor (SSRI) (escitalopram) in the first year after acute coronary syndromes (ACS). Methods: 240 pa...

Eligibility Criteria

Inclusion

  • ACS
  • Randomization within 8 weeks form index hospitalization for ACS
  • Age \> 18 years
  • Not pregnant
  • Signed informed consent

Exclusion

  • Current depression
  • Use of antidepressants \< 4 weeks
  • Previous intolerance to SSRI
  • Severe medical conditions
  • Severe heart failure
  • Alcohol or substance abuse
  • Psychosis or dementia
  • Current participation in other intervention trials
  • Pregnancy and lactation
  • Linguistic difficulties

Key Trial Info

Start Date :

November 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT00140257

Start Date

November 1 2004

Last Update

December 31 2008

Active Locations (1)

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1

Bispebjerg University Hospital

Copenhagen, Denmark, 2400 NV